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181530-09-6

181530-09-6 Structure

181530-09-6 Structure
IdentificationBack Directory
[Name]

Zinquin Ethyl Ester
[CAS]

181530-09-6
[Synonyms]

ZINQUIN ESTER
ethyl [(2-methyl-8-p-toluenesulfonylaminoquinolin-6-yloxy)acetate]
ethyl 2-(2-Methyl-8-(4-MethylphenylsulfonaMido)quinolin-6-yloxy)acetate
Acetic Acid, [[2-methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-, Ethyl Ester
Acetic acid, 2-[[2-methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-, ethyl ester
[Molecular Formula]

C21H22N2O5S
[MDL Number]

MFCD00797629
[MOL File]

181530-09-6.mol
[Molecular Weight]

414.475
Chemical PropertiesBack Directory
[Melting point ]

112-114°C
[Boiling point ]

578.0±60.0 °C(Predicted)
[density ]

1.313±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in ethanol, methanol, dimethyl sulfoxide; slightly soluble in water
[form ]

crystals
[pka]

pK1 (quinoline nitrogen): <2; pK (sulfonamide proton): 9.32 ±0.02(at 25℃)
[color ]

Colorless
[λmax]

364 nm
[Stability:]

Temperature Sensitive; Store at -20°C
[Biological Applications]

Zinc indicator; detecting apoptosis
Hazard InformationBack Directory
[Chemical Properties]

White or Pale Blue Crystalline Solid
[Uses]

A fluorescent reagent and indicator of intracellular zinc ions. An analogue of widely used indicator, TS-Q. Zinquin ethyl ester is membrane permeable therefore useful to detect intracellular zinc ions. Zinquin ethyl ester forms a complex with a zinc ion with two nitrogen atoms in the structure. Used for studying the role of zinc in apoptosis. Fluorescence: max. Abs. l = 368nm, max. Em. l = 490nm
[Uses]

A fluorescent reagent and indicator of intracellular zinc ions. An analogue of widely used indicator, TS-Q. Zinquin ethyl ester is membrane permeable therefore useful to detect intracellular zinc ions. Zinquin ethyl ester forms a complex with a zinc ion with two nitrogen atoms in the structure. Used for studying the role of zinc in apoptosis.Fluorescence: max. Abs. l = 368nm, max. Em. l = 490nm
[Uses]

Determn of intracellular Zn2+ and labile Zn2+ ions.
[storage]

Store at -20°C
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