| Identification | Back Directory | [Name]
CONCANAVALIN A TYPE III | [CAS]
11028-71-0 | [Synonyms]
CON A
nsc143504
CONCANAVALIN
CON A TYPE IV
CONCANAVALIN A
concanavalinea
A,concanavalin
CONCANAVALIN A TYPE
Concanalin A (Con A)
CONCANAVALIN A TYPE V
CONCANAVALIN A TYPE VI
CONCANAVALIN A TYPE IV
CONCANAVALIN A (CON A)
JACK BEAN HEMAGGLUTININ
CONCANAVALIN A TYPE III
CONCANAVALIN A extrapure
CONCANAVALIN A, JACK BEAN
Agglutinin from jack beans
LECTIN CANAVALIA ENSIFORMIS
Concanavalin A,from Jack bean
Concanavalin A lectin (Con A)
Concanavalin A from Jack Beans
LECTIN FROM CONCANAVALIN A TYPE VI
CONCANAVALIN A, CANAVALIA ENSIFORMIS
Lectin froM Canavalia ensiforMis lyophil.
Concanavalin A froM Concanvalia ensiforMis
CONCANAVALIN A FROM CANAVALIAENSIFORMIS TYPE V
LECTIN FROM CONCANAVALIN A PEROXIDASE*LA BELED
LECTIN FROM CANAVALIA ENSIFORMISTYPE IV- S STERILE
LECTIN FROM CANAVALIA ENSIFORMISTYPE IV- S GAMMA-IR
LECTIN CONCANAVALIN A FROM CANAVALIAENSI FORMIS FER
concanavalin a from canavalia ensiformis (jack bean)
Concanavalin A from Canavalia ensiformis (Jack bean),Con A | [EINECS(EC#)]
291-083-4 | [Molecular Formula]
C15H24 | [MDL Number]
MFCD01191475 |
| Chemical Properties | Back Directory | [Definition]
A lectin mitogen that binds specifically to and agglutinates transforms into tumors. It binds to glucose
and mannose residues in the surface. | [Appearance]
Lyophilized | [Fp ]
39 °C | [storage temp. ]
2-8°C
| [solubility ]
PBS: 5 mg/mL, slightly hazy
| [form ]
powder
| [Water Solubility ]
Slightly soluble in water and phosfate buffered saline. | [CAS DataBase Reference]
11028-71-0 |
| Hazard Information | Back Directory | [Chemical Properties]
Lyophilized | [Uses]
As a reagent in analytical and preparative biochemistry; as a probe in studies of cell surface membrane dynamics and cell division. | [Uses]
Concanavalin A is a unique lectin purified from the jack bean, C. ensiformis, that selectively cross-links cell-surface glycoproteins and affects the initiation of cell agglutination, mitogenesis, and apoptosis. Concanavalin A specifically binds to α-mannose and α-galactose structures found in sugars, glycoproteins, and glycolipids and has been used in affinity chromatography purifications of various glycoproteins and cellular structures. At 20 mg/kg concanavalin A is also used to induce liver injury in experimental mouse models of autoimmune hepatitis in order to study immune regulation by macrophages and T cells. Concanavalin A is toxic to several tumor cell lines and has been reported to induce programmed cell death of cortical neurons by a mechanism similar to that of the amyloid β peptide. | [Hazard]
Poison; teratogen; mutagen. | [General Description]
Concanavalin A is a protein containing only β-sheets in its structure, and belongs to the legume lectins family. | [Biochem/physiol Actions]
Concanavalin A is known to stimulate acute hepatic inflammation and acts as a T‐cell mitogen. It has inhibitory effect on hepatocellular carcinoma by inducing autophagy. | [storage]
Store at -20°C |
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