| Identification | Back Directory | [Name]
Benzo[b][1,8]naphthyridin-5(7H)-one, 10-(3-chlorophenyl)-6,8,9,10-tetrahydro- | [CAS]
110545-79-4 | [Synonyms]
Benzo[b][1,8]naphthyridin-5(7H)-one, 10-(3-chlorophenyl)-6,8,9,10-tetrahydro- | [Molecular Formula]
C18H15ClN2O | [MOL File]
110545-79-4.mol | [Molecular Weight]
310.78 |
| Chemical Properties | Back Directory | [Melting point ]
195-198 °C(Solv: acetonitrile (75-05-8)) | [Boiling point ]
484.6±45.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [pka]
2.18±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
SCH 40120 is a potent leukotriene inhibitor with antiinflammatory effects. SCH 40120 suppresses T cell proliferative responses, antigen-specific and poly-clonally-induced in vitro antibody responses. SCH 40120 suppresses an edematous response and inhibits the recruitment of circulating neutrophils into sites of inflammation. SCH 40120 is proming for rasearch of anti-psoriatic agents[1]. | [References]
[1] Smith SR, et al. In vitro and in vivo immunopharmacological profile of Sch 40120. Immunopharmacol Immunotoxicol. 1993 Jan;15(1):13-44. DOI:10.3109/08923979309066931 |
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