ChemicalBook--->CAS DataBase List--->1111637-74-1

1111637-74-1

1111637-74-1 Structure

1111637-74-1 Structure
IdentificationBack Directory
[Name]

1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
[CAS]

1111637-74-1
[Synonyms]

3-Acetyl-5-bromo-2-fluoropyridine
3-Acetyl-5-bromo-2-fluoropyridine 98%
1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
1-(5-Bromo-2-fluoro-3-pyridinyl)ethanone
1-(5-BroMo-2-fluoropyridine-3-yl)ethanone
1-(5-Bromo-2-fluoropyridin-3-yl)ethan-1-one
Ethanone, 1-(5-broMo-2-fluoro-3-pyridinyl)-
[EINECS(EC#)]

1533716-785-6
[Molecular Formula]

C7H5BrFNO
[MDL Number]

MFCD12024449
[MOL File]

1111637-74-1.mol
[Molecular Weight]

218.023
Chemical PropertiesBack Directory
[Boiling point ]

284.3±40.0 °C(Predicted)
[density ]

1.619±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[form ]

solid
[pka]

-4.58±0.20(Predicted)
[Appearance]

White to off-white Solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332
[Precautionary statements ]

P260-P280-P301+P312
[HS Code ]

2933399990
Spectrum DetailBack Directory
[Spectrum Detail]

1-(5-Bromo-2-fluoropyridin-3-yl)ethanone(1111637-74-1)1HNMR
Hazard InformationBack Directory
[Synthesis]

3-PyridineMethanol, 5-broMo-2-fluoro-α-Methyl-

1111637-73-0

1-(5-Bromo-2-fluoropyridin-3-yl)ethanone

1111637-74-1

The general procedure for the synthesis of 1-(5-bromo-2-fluoro-3-pyridinyl)ethanone from the compound (CAS:1111637-73-0) was as follows: pyridinium dichromate (55.4 g, 147 mmol) was dissolved in dichloromethane (DCM, 100 mL) and the solution was cooled to 0 °C. Subsequently, a solution of 1-(5-bromo-2-fluoropyridin-3-yl)ethanol (10.8 g, 49.1 mmol) in DCM (30 mL) was added to this solution. The reaction mixture was gradually warmed to room temperature and stirred continuously for 48 hours. Upon completion of the reaction, the mixture was filtered through diatomaceous earth, the filter cake was washed with DCM and the filtrate was concentrated to afford 1-(5-bromo-2-fluoropyridin-3-yl)ethanone (11 g, 51 mmol, 100% yield) as a light yellow solid. Analyzed by LC/MS (ESI+), m/z = 218 (M + H+) was measured.

[References]

[1] Patent: US2014/213581, 2014, A1. Location in patent: Paragraph 0684
[2] Patent: WO2016/123629, 2016, A1. Location in patent: Paragraph 0214
[3] Patent: WO2009/16460, 2009, A2. Location in patent: Page/Page column 54
[4] Patent: US2014/107109, 2014, A1. Location in patent: Page/Page column
[5] Patent: US2014/107109, 2014, A1. Location in patent: Page/Page column
1111637-74-1 suppliers list
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Website: www.chemicalbook.com/ShowSupplierProductsList454175/0_EN.htm
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel: +8613580539051 , +8613580539051
Website: www.yuhengpharm.com
Company Name: Neostar United (Changzhou) Industrial Co., Ltd.
Tel: +86-0519-85551759 +8613506123987 , +8613506123987
Website: http://www.neostarunited.com
Company Name: Baoji Guokang Healthchem co.,ltd
Tel: +8615604608665 15604608665 , 15604608665
Website: www.gk-bio.com
Company Name: CD Chemical Group Limited
Tel: +8615986615575 , +8615986615575
Website: http://www.codchem.com/
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418684 +8618949823763 , +8618949823763
Website: www.tnjchem.com
Company Name: Aceschem Inc.
Tel: +1-817863-6948 +1-(817)863-6948 , +1-(817)863-6948
Website: www.aceschem.com/
Company Name: Zibo Hangyu Biotechnology Development Co., Ltd
Tel: +86-0533-2185556 +8615965530500 , +8615965530500
Website: www.chemicalbook.com/manufacturer/hangyu-chemical-25178/
Company Name: Aladdin Scientific
Tel:
Website: www.aladdinsci.com/
Company Name: Suzhou ARTK Medchem Co., Ltd.
Tel: +86-512-68323658 +86-18168183658 , +86-18168183658
Website:
Company Name: Allfluoro pharmaceutical co. ltd.
Tel: +86-400-0216110 +86-15958047586 , +86-15958047586
Website: www.allfluoro.com
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-6139-8061 +86-86-13650506873 , +86-86-13650506873
Website: http://www.chemdad.com/
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Website: http://www.amadischem.com
Company Name: Shangchem Co., Ltd.  
Tel: +86-21-68182121
Website: www.chemicalbook.com/ShowSupplierProductsList14031/0_EN.htm
Company Name: Tetranov Biopharm  
Tel: 13526569071
Website: http://www.leadmedpharm.com/index.html
Company Name: shanghai Rainbow MediTech.Co.Ltd.  
Tel: 021-64968085,64968086-5815,5812 13472757003
Website: www.rainbowpharma.cn
Company Name: China Langchem Inc.  
Tel: 0086-21-58956006
Website: www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm
Tags:1111637-74-1 Related Product Information
883230-94-2 27012-25-5 953414-75-0 876161-05-6 880870-66-6 501435-91-2 1012084-53-5 36070-83-4 530141-46-9 53715-67-6 3680-69-1 116435-77-9 130369-36-7 1000341-25-2 56962-08-4 1000341-77-4 74976-31-1 197376-41-3

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.