| Identification | Back Directory | [Name]
A 63162 | [CAS]
111525-11-2 | [Synonyms]
A 63162
N-Hydroxy-N-[1-[4-(phenylmethoxy)phenyl]ethyl]acetamide
Acetamide, N-hydroxy-N-[1-[4-(phenylmethoxy)phenyl]ethyl]- | [Molecular Formula]
C17H19NO3 | [MDL Number]
MFCD00876406 | [MOL File]
111525-11-2.mol | [Molecular Weight]
285.34 |
| Hazard Information | Back Directory | [Uses]
A63162 is a specific 5-lipoxygenase (5-LOX) inhibitor. A63162 inhibits mitogen (PHA)-induced horse mononuclear cell (BMC) proliferation and inhibits Calcimycin (HY-N6687)-induced leukotriene LTB4 synthesis at the same concentration. A63162 can be used in the study of chronic obstructive pulmonary disease, arthritis and inflammatory bowel disease[1]. | [References]
[1] Olsen S C, et al. Inhibition of equine mononuclear cell proliferation and leukotriene B4 synthesis by a specific 5-lipoxygenase inhibitor, A-63162[J]. American journal of veterinary research, 1992, 53(6): 1015-1018. PMID:1320811 |
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