| Identification | Back Directory | [Name]
4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline | [CAS]
112446-99-8 | [Synonyms]
SCH43478
SCH-43478
SCH 43478
4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline | [Molecular Formula]
C12H10ClN3O | [MDL Number]
MFCD00933440 | [MOL File]
112446-99-8.mol | [Molecular Weight]
247.68 |
| Chemical Properties | Back Directory | [Melting point ]
232-236 °C(Solv: chloroform (67-66-3)) | [Boiling point ]
468.2±40.0 °C(Predicted) | [density ]
1.418±0.06 g/cm3(Predicted) | [pka]
9.04±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
SCH-43478 is a non-?nucleoside antiviral agent. It has potent and selective activity against herpes simplex virus type 2 (HSV-?2). | [Uses]
SCH-43478 is a non-nucleoside antiviral agent. SCH-43478 shows potent and selective activity against herpes simplex virus type 2 (HSV-2) with an IC50 of 1.8 μg/mL using Vero cells. SCH-43478 demonstrates significant efficacy in the guinea pig genital model of HSV infection[1]. | [IC 50]
HSV-2: 1.8 μg/mL (IC50) | [References]
[1] R Albin, et al. SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2. Antiviral Res. 1997 Aug;35(3):139-46. DOI:10.1016/s0166-3542(97)00023-5 |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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