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112668-56-1

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112668-56-1 Structure

112668-56-1 Structure
IdentificationBack Directory
[Name]

3'-Deoxy-3'-fluoro-5-fluorouridine
[CAS]

112668-56-1
[Synonyms]

Uridine, 3'-deoxy-3',5-difluoro-
3’-Deoxy-3’-fluoro-5-fluorouridine
3'-Deoxy-3'-fluoro-5-fluorouridine
[Molecular Formula]

C9H10F2N2O5
[MDL Number]

MFCD28975240
[MOL File]

112668-56-1.mol
[Molecular Weight]

264.18
Chemical PropertiesBack Directory
[density ]

1.69±0.1 g/cm3(Predicted)
[pka]

7.63±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

3’-Deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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