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125217-37-0

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125217-37-0 Structure

125217-37-0 Structure
IdentificationBack Directory
[Name]

3'-Deoxy-3'-fluoro-5-Methyluridine
[CAS]

125217-37-0
[Synonyms]

3'-F-5-Me-Uridine
3’-Deoxy-3’-fluoro-5-methyluridine
3'-Deoxy-3'-fluoro-5-Methyluridine
Uridine, 3'-deoxy-3'-fluoro-5-methyl- (9CI)
1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)thymine
[Molecular Formula]

C10H13FN2O5
[MDL Number]

MFCD27921028
[MOL File]

125217-37-0.mol
[Molecular Weight]

260.22
Hazard InformationBack Directory
[Uses]

3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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