| Identification | Back Directory | [Name]
3'-Deoxy-3'-fluoro-5-Methyluridine | [CAS]
125217-37-0 | [Synonyms]
3'-F-5-Me-Uridine
3’-Deoxy-3’-fluoro-5-methyluridine
3'-Deoxy-3'-fluoro-5-Methyluridine
Uridine, 3'-deoxy-3'-fluoro-5-methyl- (9CI)
1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)thymine | [Molecular Formula]
C10H13FN2O5 | [MDL Number]
MFCD27921028 | [MOL File]
125217-37-0.mol | [Molecular Weight]
260.22 |
| Hazard Information | Back Directory | [Uses]
3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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