ChemicalBook--->CAS DataBase List--->112749-52-7

112749-52-7

112749-52-7 Structure

112749-52-7 Structure
IdentificationBack Directory
[Name]

4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one
[CAS]

112749-52-7
[Synonyms]

EcDsbB-IN-12
4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one
3(2H)-Pyridazinone, 4,5-dichloro-2-[(2-chlorophenyl)methyl]-
4,5-Dichloro-2-[(2-chlorophenyl)methyl]-2,3-dihydropyridazin-3-one
[Molecular Formula]

C11H7Cl3N2O
[MDL Number]

MFCD02081599
[MOL File]

112749-52-7.mol
[Molecular Weight]

289.55
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H302-H319-H332-H335
[Precautionary statements ]

P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard InformationBack Directory
[Description]

EcDsbB-IN-12 is a novel potent specific inhibitor of EcDsbB, targeting disulfide bond forming enzyme.
[Uses]

4,5-dichloro-2-[(2-chlorophenyl)methyl]-2,3-dihydropyridazin-3-one (cas# 112749-52-7) is a chemical compound that was found to be an in inhibitor of virulence-promoting enzyme such as DsbB, which is a cytoplasmic membrane protein able to generate disulfide bond in proteins (to make them more stable). Another study showed that this compound possesses both: antimicrobial and antibacterial activities, which suggests that it can be used for therapeutic purposes.
Spectrum DetailBack Directory
[Spectrum Detail]

4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one(112749-52-7)1HNMR
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