| Identification | More | [Name]
L(+)-Gulonic acid gamma-lactone | [CAS]
1128-23-0 | [Synonyms]
L-(+)-GULONIC ACID GAMMA-LACTONE
L-GULONIC ACID GAMMA-LACTONE
L-GULONIC GAMMA-LACTONE
L-GULONIC-G-LACTONE
L(+)-GULONO-1,4-LACTONE
L-GULONO-1,4-LACTONE
L-GULONO-GAMMA-LACTONE
L-GULONOLACTONE
L-Gulonic acid γ-lactone
L(+)-GULONIC ACID GAMMA-LACTONE 97%
L-GulonicAcid-y-Lactone
L-Gulonicacid-1,4-lactone
(3S,4S,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-oxolan-2-one
L-(+)-GLUTONIC ACID GAMMA-LACTONE
L-(+)-GLUTONIC ACID-LACTONE
L-GULONO-1,4-LACTONE extrapure
L-Gulonic acid γ-lactone, L-(+)-Gulono-1,4-lactone
(3S)-3β,4β-Dihydroxy-5β-[(S)-1,2-dihydroxyethyl]-4,5-dihydro-2(3H)-furanone | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C6H10O6 | [MDL Number]
MFCD00064331 | [Molecular Weight]
178.14 | [MOL File]
1128-23-0.mol |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
187-190 °C(lit.)
| [alpha ]
54.5 º (c=2, water 57.5 ºC) | [Boiling point ]
230.35°C (rough estimate) | [density ]
1.3253 (rough estimate) | [refractive index ]
56 ° (C=2, H2O) | [storage temp. ]
0-6°C | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Sparingly) | [form ]
Viscous Solution | [pka]
12.06±0.60(Predicted) | [color ]
White to Off-white | [Optical Rotation]
[α]19/D +55°, c = 4 in H2O | [Water Solubility ]
Soluble in water | [BRN ]
83002 | [InChI]
InChI=1/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3+,4-,5+/s3 | [InChIKey]
SXZYCXMUPBBULW-QICJDPMJNA-N | [SMILES]
[C@H]1([C@@H](O)CO)OC(=O)[C@@H](O)[C@H]1O |&1:0,1,8,10,r| | [CAS DataBase Reference]
1128-23-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29400090 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
L-Gulono-1,4-lactone is a precursor in the biosynthesis of ascorbic acid, one of the many forms of Vitamin C. | [Definition]
ChEBI: L-gulono-1,4-lactone is the furanose form of gulonolactone having L-configuration. It has a role as a human metabolite and a mouse metabolite. It is functionally related to a L-gulonic acid. | [Synthesis]
The general procedure for the synthesis of L-gulosonic acid-γ-lactone from L-ascorbic acid was as follows: 10% Pd/C catalyst (8.3 g) was added to a solution of L-ascorbic acid (83.9 g, 0.477 mol) in water (600 mL). The reaction mixture was placed in a Parr hydrogenator and hydrogenated for 62 hours at 48 psi hydrogen pressure and 18°C. Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst and the filtrate was concentrated under vacuum to afford L-gulosonic acid-γ-lactone (81.0 g, 96% yield) as an off-white solid. The resulting solid was dried in a vacuum oven at 50 °C for 18 h. The melting point was measured to be 182-184 °C. | [storage]
Store at 2-8°C | [References]
[1] Journal of Organic Chemistry, 1981, vol. 46, # 14, p. 2976 - 2977
[2] Patent: US2004/54172, 2004, A1
[3] Patent: US2003/232889, 2003, A1. Location in patent: Page/Page column 12
[4] Synlett, 2017, vol. 28, # 8, p. 970 - 972
[5] Tetrahedron Asymmetry, 1996, vol. 7, # 9, p. 2711 - 2720 |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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