| Identification | Back Directory | [Name]
INDO 1-AM | [CAS]
112926-02-0 | [Synonyms]
INDO 1-AM
Indo-1-ame
Indo 1 Am Ester
INDO 1-AM SOLUTION
Indo-1, AM *SP-Pak*
INDO 1/AM (1SET = 10x100UG)
INDO 1-AM, FOR FLUORESCENCE
Indo-1, AM *CAS 112926-02-0*
indo-1pentaacetoxymethylester
ACETOXYMETHYL ESTER OF INDO 1
INDO 1-AM >93% FLUORESCENT MARKER FO
Indo-1, AM *UltraPure Grade* *CAS 112926-02-0*
Ind)-3-(p-nitrophenyl)-5-phenyltetrazolium Chloride
P-iodonitrotetrazolium Violet O 1 Acetoxymethyl Ester
3(p-nitrophenyl)-2-(p-iodophenyl)-5-phenyltetrazolium Chloride
4-(6-Carboxy-2-indolyl)-4'-methyl-2,2'-(ethylenedioxy)dianiline-
4-(6-CARBOXY-2-INDOLYL)-4'-METHYL-2,2'-(ETHYLENEDIOXY)DIANILINE-N,N,N',N'-TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL) ESTER
1-[2-Amino-5-(6-carboxy-2-indolyl)phenoxy]-2-(2-amino-5-methylphenoxy)ethane-N,N,N',N'-tetraaceticacid,pentaacetoxymethylester
1-[2-AMINO-5-(6-CARBOXYINDOL-2-YL)PHENOXY]-2-(2'-AMINO-5'-METHYLPHENOXY) ETHANE-N,N,N,N-TETRAACETIC ACID PENTAACETOXY-METHYL ESTER
1-[2-AMINO-5-(6-CARBOXYINDOL-2-YL)PHENOXY]-2-(2'-AMINO-5'-METHYLPHENOXY) ETHANE-N,N,N',N'-TETRAACETIC ACID PENTAACETOXYMETHYL ESTER
2-[4-[Bis[2-[(acetoxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid (acetoxy)methyl ester
2-[4-[Bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoetyl]amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid (acetyloxy)methyl ester
1H-Indole-6-carboxylic acid, 2-[4-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-, (acetyloxy)methyl ester | [Molecular Formula]
C47H51N3O22 | [MDL Number]
MFCD00036955 | [MOL File]
112926-02-0.mol | [Molecular Weight]
1009.91 |
| Chemical Properties | Back Directory | [Melting point ]
>250 ℃ | [Boiling point ]
1009.2±65.0 °C(Predicted) | [density ]
1.374±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMSO: soluble
| [form ]
powder | [pka]
14.85±0.30(Predicted) | [color ]
Light yellow | [Appearance]
Solid Powder | [λmax]
356nm | [Biological Applications]
Calcium indicator; preventing arrhythmias | [InChIKey]
CAWBRCOBJNWRLK-UHFFFAOYSA-N | [SMILES]
CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)c1ccc(C)cc1OCCOc2cc(ccc2N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)-c3cc4ccc(cc4[nH]3)C(=O)OCOC(C)=O |
| Hazard Information | Back Directory | [Description]
Indo-1 AM is a cell-permeant acetoxymethyl ester of indo-1, a ratiometric fluorescent calcium indicator. Indo-1 AM is hydrolyzed by intracellular esterases to release Indo-1 in cells. Indo-1 is commonly used in flow cytometry. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when indo-1 binds calcium. | [Chemical Properties]
yellow solid | [Uses]
Cell-permeant derivative of Indo 1. Indo 1-AM is fluorescent probe for Ca2+. After crossing the membrane, the product is rapidly hydrolyzed by cytoplasmic esterases to the membrane impermeant INDO 1. Indo 1-AM is possible using for ratiometric fluorescenc | [storage]
-20°C | [Excitation / Emission Maximum]
349-364 nm/475-485 nm (no Ca2+), 400-410 nm (Ca2+-bound) |
|
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