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1130067-18-3

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1130067-18-3 Structure

1130067-18-3 Structure
IdentificationBack Directory
[Name]

N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthaMide
[CAS]

1130067-18-3
[Synonyms]

VU0155056
N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthaMide
2-Naphthalenecarboxamide, N-[2-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-
N-(2-{4-[2-OXO-2,3-DIHYDRO-1H-BENZO(D)IMIDAZOL-1-YL]PIPERIDIN-1-YL}ETHYL)-2-NAPHTHAMIDE;VU0155056
[Molecular Formula]

C25H26N4O2
[MDL Number]

MFCD22416857
[MOL File]

1130067-18-3.mol
[Molecular Weight]

414.5
Chemical PropertiesBack Directory
[density ]

1.257±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

powder
[pka]

12.04±0.30(Predicted)
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

VU0155056 has been used as a phospholipase D-1 (PLD1) inhibitor:
  • to study its role in regulated exocytosis
  • to test bacterial and human PLD enzymes for specificity of inhibition
  • in neuro-2a (N2a) cell culture and survival assay

[Definition]

ChEBI: N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-2-naphthalenecarboxamide is a naphthalenecarboxamide.
[Biological Activity]

VU0155056 or N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl ethyl)-2-naphthamide is a cell permeable phospholipase D (PLD) inhibitor. It inhibits both PLD1 and PLD2.
Spectrum DetailBack Directory
[Spectrum Detail]

N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthaMide(1130067-18-3)1HNMR
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