| Identification | Back Directory | [Name]
valilactone | [CAS]
113276-96-3 | [Synonyms]
valilactone
(-)-Valilactone
(2S)-N-Formyl-L-valine 1-[[(2S)-3α-hexyl-4-oxooxetan-2β-yl]methyl]hexyl ester
L-Valine, N-formyl-, (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]hexyl ester | [Molecular Formula]
C22H39NO5 | [MDL Number]
MFCD12032161 | [MOL File]
113276-96-3.mol | [Molecular Weight]
397.55 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 10 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
Valilactone is a fatty acid synthase inhibitor produced by a cultured strain of soil actinomycetes. Fatty acid synthase (FAS) is necessary for growth and survival of tumor cells and is a promising drug target for oncology. | [Uses]
Valilactone is a potent and effective inhibitor of esterase, produced by actinomycetes[1]. | [storage]
Store at -20°C | [References]
[1] Kitahara M, et al. Valilactone, an inhibitor of esterase, produced by actinomycetes. J Antibiot (Tokyo). 1987;40(11):1647-1650. DOI:10.7164/antibiotics.40.1647 |
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