ChemicalBook--->CAS DataBase List--->1138-80-3

1138-80-3

1138-80-3 Structure

1138-80-3 Structure
IdentificationMore
[Name]

N-Carbobenzyloxyglycine
[CAS]

1138-80-3
[Synonyms]

2-([(BENZYLOXY)CARBONYL]AMINO)ACETIC ACID
BENZYLOXYCARBONYL-GLYCINE
CARBOBENZYLOXYGLYCINE
CBZ-GLY
CBZ-GLYCINE
CBZ-GLY-OH
LABOTEST-BB LT00005891
N-ALPHA-BENZYLOXYCARBONYL-GLYCINE
N-ALPHA-CARBOBENZOXY-GLYCINE
N-ALPHA-CBZ-GLYCINE
N-BENZYLOXYCARBONYLGLYCINE
N-CARBOBENZOXYGLYCINE
N-CARBOBENZYLOXYGLYCINE
N-CBZ-GLYCINE
N-CBZ-GLYCINE-OH
RARECHEM AL BO 0395
TIMTEC-BB SBB003458
Z-GLYCINE
Z-GLY-OH
Z-L-GLYCINE
[EINECS(EC#)]

214-516-0
[Molecular Formula]

C10H11NO4
[MDL Number]

MFCD00002691
[Molecular Weight]

209.2
[MOL File]

1138-80-3.mol
Chemical PropertiesBack Directory
[Appearance]

white to light yellow crystal powde
[Melting point ]

118-122 °C(lit.)
[Boiling point ]

348.55°C (rough estimate)
[density ]

1.2944 (rough estimate)
[refractive index ]

1.5400 (estimate)
[storage temp. ]

Store at RT.
[solubility ]

methanol: 0.1 g/mL, clear
[form ]

Fine Crystalline Powder
[pka]

3.98±0.10(Predicted)
[color ]

White
[Water Solubility ]

Soluble in methanol. Insoluble in water.
[BRN ]

526877
[Major Application]

peptide synthesis
[InChI]

InChI=1S/C10H11NO4/c12-9(13)6-11-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
[InChIKey]

CJUMAFVKTCBCJK-UHFFFAOYSA-N
[SMILES]

C(O)(=O)CNC(OCC1=CC=CC=C1)=O
[CAS DataBase Reference]

1138-80-3(CAS DataBase Reference)
[EPA Substance Registry System]

1138-80-3(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H315-H335
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
[Hazard Codes ]

Xn
[Risk Statements ]

R62:Possible risk of impaired fertility.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[RTECS ]

MB9129000
[TSCA ]

Yes
[REACH Registrations]

Active
[HS Code ]

29242995
[Storage Class]

11 - Combustible Solids
[Safety Profile]

and dyspnea. A severe eye and moderate
[Toxicity]

mouse,LD50,intravaginal,380mg/kg (380mg/kg),Journal of Pharmaceutical Sciences. Vol. 68, Pg. 696, 1979.
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Glycine-->Benzyl chloroformate-->Congo Red
[Preparation Products]

N-Benzyloxycarbonylglycine thioamide-->Z-Gly-Gly-Phe-OH-->Z-Gly-ONp-->2,5-Oxazolidinedione-->2-amino-N,N-dimethylacetamide-->N-Cbz-3-oxoazetidine-->Z-Gly-NH2-->N-[(Benzyloxy)carbonyl]glycine pentachlorophenyl ester-->Serine,N-[(phenylmethoxy)carbonyl]glycyl-O-ethyl-3-oxo-, ethyl ester (9CI)-->Benzyl N-[(cyclopropylcarbaMoyl)Methyl]carbaMate
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Benzyloxycarbonyl glycine(1138-80-3).msds
Hazard InformationBack Directory
[Chemical Properties]

N-Carbobenzyloxyglycine is white to light yellow crystal powde
[Uses]

N-Carbobenzoxyglycine is used in the dipeptide synthesis.
[Definition]

N-Carbobenzyloxyglycine is a derivative of glycine having a benzyloxycarbonyl protecting group attached to the nitrogen.
[reaction suitability]

reaction type: solution phase peptide synthesis
Spectrum DetailBack Directory
[Spectrum Detail]

N-Carbobenzyloxyglycine(1138-80-3)MS
N-Carbobenzyloxyglycine(1138-80-3)1HNMR
N-Carbobenzyloxyglycine(1138-80-3)IR1
N-Carbobenzyloxyglycine(1138-80-3)IR2
N-Carbobenzyloxyglycine(1138-80-3)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

N-Carbobenzyloxyglycine, 98.50%(1138-80-3)
[Alfa Aesar]

N-Benzyloxycarbonylglycine, 98+%(1138-80-3)
[TCI AMERICA]

N-Carbobenzoxyglycine,>98.0%(LC)(T)(1138-80-3)
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