| Identification | Back Directory | [Name]
Ciwujianoside C3 | [CAS]
114906-74-0 | [Synonyms]
Ciwujianoside C3
Olean-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)- | [Molecular Formula]
C53H86O21 | [MDL Number]
MFCD32671368 | [MOL File]
114906-74-0.mol | [Molecular Weight]
1059.24 |
| Chemical Properties | Back Directory | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
12.50±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the dried rhizome of Acanthopanax senticosus. | [Uses]
Ciwujianoside?C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax?henryi Harms. Ciwujianoside?C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2]. | [in vivo]
| Animal Model: | Mice[1] | | Dosage: | 0.5 mg/kg | | Administration: | Oral administration; 0.5 mg/kg/day; 17 days | | Result: | Reinforced object recognition memory. |
| [References]
[1] Kang DH, et al. Anti-inflammatory effects of Ciwujianoside C3, extracted from the leaves of Acanthopanax henryi (Oliv.) Harms, on LPS-stimulated RAW 264.7 cells. Mol Med Rep. 2016 Oct;14(4):3749-58. DOI:10.3892/mmr.2016.5710
[2] Yamauchi Y, et al. Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain.Nutrients. 2019 May 22;11(5). DOI:10.3390/nu11051142 |
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