| Identification | Back Directory | [Name]
CB-86 | [CAS]
1150586-64-3 | [Synonyms]
CB-86
Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-hydroxyphenoxy]- | [Molecular Formula]
C26H43NO3 | [MDL Number]
MFCD18382107 | [MOL File]
1150586-64-3.mol | [Molecular Weight]
417.62 |
| Hazard Information | Back Directory | [Description]
CB-86 is a resorcinol-anandamide hybrid compound that acts as a partial agonist for the central cannabinoid (CB1) receptor and a neutral antagonist for the peripheral cannabinoid (CB2) receptor with Ki values of 5.6 and 7.9 nM, respectively.1 Its demonstrated potency is similar to that of WIN 55,212-2 (Ki = 21 and 2.1 nM for CB1 and CB2, respectively).1 CB-86 (1 mg/kg) exhibits antinociceptive effects in mice treated with formalin.1 | [References]
1. Brizzi, A., Brizzi, V., Cascio, M.G., et al. New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo J. Med. Chem. 52,2506-2514(2009). |
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| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|