| Identification | Back Directory | [Name]
(23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one | [CAS]
115404-57-4 | [Synonyms]
Niloticin
(23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one
Lanost-7-en-3-one,24,25-epoxy-23-hydroxy-, (13a,14b,17a,20S,23R,24S)-
Lanost-7-en-3-one, 24,25-epoxy-23-hydroxy-, (13α,14β,17α,20S,23R,24S)- | [Molecular Formula]
C30H48O3 | [MDL Number]
MFCD20260343 | [MOL File]
115404-57-4.mol | [Molecular Weight]
456.71 |
| Chemical Properties | Back Directory | [Melting point ]
149-151 °C | [Boiling point ]
538.5±45.0 °C(Predicted) | [density ]
1.07±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Cryst. | [pka]
14.37±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways[1]. | [References]
[1] Xu H, et al. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways. Biomed Pharmacother. 2022 May;149:112902. DOI:10.1016/j.biopha.2022.112902 |
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| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
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