| Identification | Back Directory | [Name]
(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one | [CAS]
33457-62-4 | [Synonyms]
Alnustone
Alnvstone
(4E,6E)-1,7-diphenylhepta-4,6-dien-3-one
(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
4,6-Heptadien-3-one, 1,7-diphenyl-, (4E,6E)- | [Molecular Formula]
C19H18O | [MDL Number]
MFCD00926095 | [MOL File]
33457-62-4.mol | [Molecular Weight]
262.35 |
| Chemical Properties | Back Directory | [Melting point ]
60.5-61℃ | [Boiling point ]
442.9±34.0 °C(Predicted) | [density ]
1.058±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Soluble in DMSO and methanol; | [form ]
Powder | [color ]
White to yellow | [Water Solubility ]
insoluble in water | [Stability:]
Light Sensitive | [InChI]
1S/C19H18O/c20-19(16-15-18-11-5-2-6-12-18)14-8-7-13-17-9-3-1-4-10-17/h1-14H,15-16H2/b13-7+,14-8+ | [InChIKey]
OWMJDOUOHDOUFG-FNCQTZNRSA-N | [SMILES]
O=C(CCc2ccccc2)\C=C\C=C\c1ccccc1 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow needle-shaped crystals, soluble in methanol and ethanol, derived from the rhizomes and seeds of Alnus fragrans; flowers of Alnus serrata; and rhizomes of Curcuma longa. | [Uses]
Alnustone is a naturally occuring compound that is found in the rhizomes of Curcuma xanthorrhiza, a plant used in Indonesian folk medicine for its analgesic effects. Alnustone exhibits anti-inflammatory, antihepatotoxic and antiemetic activities. | [Definition]
ChEBI: Alnustone is a diarylheptanoid. | [Biological Activity]
Alnustone is a diarylheptanoid isolated from Alpinia katsumadai Hayatarhizomes of Curcuma xanthorrhiza and other plants th at exhibits anti-hyperglycemicanti-inflammatoryantihepatotoxic and antiemetic activities. Alnustone is a potent inhibitor of the Thyroid Adenoma Associated (THADA) functionwhich reverses THADA-induced β-cell dysfunction and ameliorate hyperglycemia in obese mice. It significantly decreases fed blood glucose and improved glucose tolerance in mice. | [target]
Immunology & Inflammation related |
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