ChemicalBook--->CAS DataBase List--->1159174-80-7

1159174-80-7

1159174-80-7 Structure

1159174-80-7 Structure
IdentificationBack Directory
[Name]

Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[4-(acetylamino)-2-oxo-1(2H)-pyrimidinyl]-1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]ethyl 2-cyanoethyl ester
[CAS]

1159174-80-7
[Synonyms]

N4-Ac-C-(S)-GNA phosphoramidite
N4-acetyl-(S)-1- (4, 4'-dimethoxytrityl)-3-cytidine-2-cyanoethyl Phosphoramidite
(S)-1-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl)diisopropylphosphoramidite
Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[4-(acetylamino)-2-oxo-1(2H)-pyrimidinyl]-1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]ethyl 2-cyanoethyl ester
[Molecular Formula]

C39H48N5O7P
[MOL File]

1159174-80-7.mol
[Molecular Weight]

729.81
Chemical PropertiesBack Directory
[pka]

10.43±0.20(Predicted)
[InChIKey]

GJBIWQXFRRQYML-MVYUDSRYNA-N
[SMILES]

C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H](CN1C=CC(NC(=O)C)=NC1=O)OP(OCCC#N)N(C(C)C)C(C)C |&1:25,r|
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Uses]

N4-Ac-C-(S)-GNA phosphoramidite is an important intermediate for the synthesis of nucleic acids and their analogs[1].
[References]

[1] Christensen MS, et al. Synthetic nucleic acid secondary structures containing the four stereoisomers of 1,4-bis(thymine-1-yl)butane-2,3-diol. Org Biomol Chem. 2008 Jan 7;6(1):81-91. DOI:10.1039/b713888a
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