| Identification | Back Directory | [Name]
6-Bromoimidazo[1,2-b]pyri... | [CAS]
1159977-65-7 | [Synonyms]
6-Bromoimidazo[1,2-b]pyri...
6-BroMoiMidazo[1,2-b]pyridazin
6-BroMoiMidazo[1,2-b]pyridazine
Imidazo[1,2-b]pyridazine, 6-bromo- | [Molecular Formula]
C6H4BrN3 | [MDL Number]
MFCD12198219 | [MOL File]
1159977-65-7.mol | [Molecular Weight]
198.02 |
| Chemical Properties | Back Directory | [density ]
1.89±0.1 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [pka]
3.60±0.30(Predicted) | [Appearance]
Off-white to light brown Solid | [CAS DataBase Reference]
1159977-65-7 |
| Hazard Information | Back Directory | [Synthesis]
GENERAL STEPS: To a solution of 6-bromopyridazin-3-amine (3.48 g, 20 mmol) in ethanol/water (5:1, 180 mL) was added 2-bromo-1,1-diethoxyethane (11.8 g, 60 mmol) followed by p-toluenesulfonic acid (20.6 mg, 0.12 mmol). The reaction mixture was stirred at 80 °C for 16 h. After completion of the reaction, the solvent was concentrated in vacuum by rotary evaporator. The resulting solid was washed with distilled water (4 mL), collected by filtration through a Büchner funnel and dried overnight in a vacuum oven at 40 °C to afford 6-bromoimidazo[1,2-b]pyridazine as a gray solid (3.9 g, 100% yield). Mass spectrum (ESI, positive ion mode) m/z: 198.1 [M + H]+; 1H NMR (400 MHz, CDCl3): δ 8.71 (d, J = 9.6 Hz, 1H), 8.44 (d, J = 1.6 Hz, 1H), 8.33 (d, J = 1.9 Hz, 1H), 7.97 (d, J = 9.6 Hz, 1H). | [References]
[1] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0288 |
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| Company Name: |
Shanghai Uchem Inc.
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| Telephone: |
15618758386 15618758386 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList15300/0_EN.htm |
| Company Name: |
SPIRO PHARMA
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| Telephone: |
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| Website: |
www.spiropharma.com.cn |
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