| Identification | More | [Name]
3-Hydroxy-2,4,5-trifluorobenzoic acid | [CAS]
116751-24-7 | [Synonyms]
2,4,5-TRIFLUORO-3-HYDROXYBENZOIC ACID
3-HYDROXY-2,4,5-TRIFLUOROBENZOIC ACID
2,4,5-Trifluoro-3-Hydroxybenzo
3-Hydroxy-2,4,5-trifluorobenzoic acid ,98% | [Molecular Formula]
C7H3F3O3 | [MDL Number]
MFCD00800378 | [Molecular Weight]
192.09 | [MOL File]
116751-24-7.mol |
| Questions And Answer | Back Directory | [Synthesis]
3-Hydroxy-2,4,5-trifluorobenzoic acid was synthesized from m-aminobenzoic acid via a three-step reaction involving halogenation, diazotization, and hydrolysis. The synthetic route is shown in the figure below. 
Figure 1 Synthetic route of 3-Hydroxy-2,4,5-trifluorobenzoic acid |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
143-147 °C(lit.)
| [Boiling point ]
292.6±40.0 °C(Predicted) | [density ]
1.699±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C, stored under nitrogen | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
2.75±0.10(Predicted) | [color ]
White to Almost white | [Detection Methods]
HPLC,NMR | [InChI]
InChI=1S/C7H3F3O3/c8-3-1-2(7(12)13)4(9)6(11)5(3)10/h1,11H,(H,12,13) | [InChIKey]
YYAFUGSJSHXYNK-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC(F)=C(F)C(O)=C1F | [CAS DataBase Reference]
116751-24-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29182900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
2,4,5-Trifluoro-3-hydroxybenzoic Acid can be used to prepare quinoline derivatives as Antibacterial Agents. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
|