| Identification | Back Directory | [Name]
(S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate | [CAS]
1171197-20-8 | [Synonyms]
mk4827 int
BARICITINIB INT
MK4827 intermediate
(S)-4-(1-Boc-3-piperidyl)aniline
(S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
tert-butyl (S)-3-(4-aminophenyl)piperidine-1-carboxylate
tert-butyl (3S)-3-(4-aminophenyl)piperidine-1-carboxylate
(3S)-3-(4-aminophenyl)piperidine-1-carboxylic acid tert-butyl ester
2-Methyl-2-propanyl (3S)-3-
(4-aminophenyl)-1-piperidinecarboxylate
(3S)-3-(4-Aminophenyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
1-Piperidinecarboxylic acid, 3-(4-aminophenyl)-, 1,1-dimethylethyl ester, (3S)- | [Molecular Formula]
C16H24N2O2 | [MDL Number]
MFCD27921195 | [MOL File]
1171197-20-8.mol | [Molecular Weight]
276.374 |
| Chemical Properties | Back Directory | [Boiling point ]
412.7±45.0 °C(Predicted) | [density ]
1.100±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
4.96±0.10(Predicted) | [Appearance]
White to off-white Solid | [InChI]
InChI=1S/C16H24N2O2/c1-16(2,3)20-15(19)18-10-4-5-13(11-18)12-6-8-14(17)9-7-12/h6-9,13H,4-5,10-11,17H2,1-3H3/t13-/m1/s1 | [InChIKey]
SWUANUQBXJNXGP-CYBMUJFWSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCC[C@@H](C2=CC=C(N)C=C2)C1 |
| Hazard Information | Back Directory | [Uses]
(S)-tert-Butyl 3-(4-Aminophenyl)piperidine-1-carboxylate is an impurity of Niraparib, a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. |
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