| Identification | Back Directory | [Name]
SOPHORAISOFLAVONEA | [CAS]
117204-81-6 | [Synonyms]
SOPHORAISOFLAVONEA
Allolicoisoflavone B
3-(2,2-Dimethyl-5-hydroxy-2H-1-benzopyran-8-yl)-5,7-dihydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)- | [Molecular Formula]
C20H16O6 | [MDL Number]
MFCD32222467 | [MOL File]
117204-81-6.mol | [Molecular Weight]
352.34 |
| Chemical Properties | Back Directory | [Melting point ]
235-237℃ | [Boiling point ]
611.2±55.0 °C(Predicted) | [density ]
1.443±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
6.38±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation[1]. | [References]
[1] Lin Y, et, al. Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. Bioorg Med Chem. 2017 Jul 15;25(14):3706-3713. DOI:10.1016/j.bmc.2017.05.009 |
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