ChemicalBook--->CAS DataBase List--->1184940-47-3

1184940-47-3

1184940-47-3 Structure

1184940-47-3 Structure
IdentificationBack Directory
[Name]

(alphaR)-3,5-Difluoro-alpha-hydroxybenzeneacetic acid 2-(2-ethyl-4-hydroxy-3-methylbenzoyl)hydrazide
[CAS]

1184940-47-3
[Synonyms]

EMD638683 (R-Form)
EMD638683 R Form,EMD638683 RForm,EMD-638683 R-Form
Benzeneacetic acid, 3,5-difluoro-α-hydroxy-, 2-(2-ethyl-4-hydroxy-3-methylbenzoyl)hydrazide, (αR)-
(alphaR)-3,5-Difluoro-alpha-hydroxybenzeneacetic acid 2-(2-ethyl-4-hydroxy-3-methylbenzoyl)hydrazide
[Molecular Formula]

C18H18F2N2O4
[MDL Number]

MFCD22417082
[MOL File]

1184940-47-3.mol
[Molecular Weight]

364.34
Chemical PropertiesBack Directory
[Boiling point ]

657.6±55.0 °C(Predicted)
[density ]

1.363
[form ]

Solid
[pka]

8.68±0.25(Predicted)
[color ]

Off-white to pink
Hazard InformationBack Directory
[Uses]

EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.
[References]

[1] Ackermann TF, et al. EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011;28(1):137-46. DOI:10.1159/000331722
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