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1186430-60-3

1186430-60-3 Structure

1186430-60-3 Structure
IdentificationBack Directory
[Name]

Antihistamine-1
[CAS]

1186430-60-3
[Synonyms]

Antihistamine-1
1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-2-[4-(4-methyl-1H-pyrazol-1-yl)-1-piperidinyl]-
[Molecular Formula]

C23H24FN5
[MDL Number]

MFCD30533323
[MOL File]

1186430-60-3.mol
[Molecular Weight]

389.47
Chemical PropertiesBack Directory
[Boiling point ]

596.0±60.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

7.66±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

1-[(4-Fluorophenyl)methyl]-2-[4-(4-methyl-1H-pyrazol-1-yl)-1-piperidinyl]-1H-benzimidazole, is a 2-aminobenzimidazole H1-antihistamines used for the treatment of insomnia. It is also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM.
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