| Identification | Back Directory | [Name]
2-hydroxy-4-oxo-pentanedioic acid | [CAS]
1187-99-1 | [Synonyms]
DL-KHG Li
2-keto-4-hydroxyglutarate
DL-4-Hydroxy-2-ketoglutarate
4-Hydroxy-2-oxoglutaric acid
2-hydroxy-4-oxo-pentanedioic acid
Pentanedioic acid, 2-hydroxy-4-oxo-
4-Hydroxy-2-oxoglutaric acid lithium salt
DL-4-Hydroxy-2-ketoglutarate disodium salt
DL-4-Hydroxy-2-ketoglutarate DilithiuM Salt
DL-4-Hydroxy-2-ketoglutaric acid lithium salt | [Molecular Formula]
C5H6O6 | [MDL Number]
MFCD18382351 | [MOL File]
1187-99-1.mol | [Molecular Weight]
162.1 |
| Chemical Properties | Back Directory | [Melting point ]
>250°C (dec.) | [Boiling point ]
425.6±35.0 °C(Predicted) | [density ]
1.700±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Water | [form ]
Solid | [pka]
2.34±0.54(Predicted) | [color ]
Off-White | [BRN ]
1780096 | [InChI]
1S/C5H6O6/c6-2(4(8)9)1-3(7)5(10)11/h2,6H,1H2,(H,8,9)(H,10,11) | [InChIKey]
WXSKVKPSMAHCSG-UHFFFAOYSA-N | [SMILES]
OC(CC(=O)C(=O)O)C(=O)O |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A 4-substituted analog of Glutamic acid. This compound is a good enzyme substrate for GOT (glutamic oxalacetic aminotransferase). | [Definition]
ChEBI: An oxo dicarboxylic acid comprising glutaric acid having oxo- and hydroxy substituents at the 2- and 4-positions respectively. | [Biological Activity]
DL-4-Hydroxy-2-ketoglutaric acid (DL-KHG) is an enzyme substrate for GOT (glutamic oxalacetic aminotransferase) and 2-Keto-4-hydroxyglutarate aldolasewhich catalyzes the reversible cleavage of 2-keto-4-hydroxyglutarate yielding pyruvate plus glyoxylate; DL-KHG has been used in mass spectrometry for the rapid analysis of negatively charged water-soluble cellular metabolites. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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