ChemicalBook--->CAS DataBase List--->1189960-80-2

1189960-80-2

1189960-80-2 Structure

1189960-80-2 Structure
IdentificationBack Directory
[Name]

N-Desethylamiodarone-D4 HCl
[CAS]

1189960-80-2
[Synonyms]

N-Desethylamiodarone-D4 HCl
N-Desethylamiodarone hydrochloride salt
[2H4]-N-Desethylamiodarone hydrochloride
N-Desethylamiodarone-D4 hydrochloride solution
Amiodarone EP Impurity B-d4 HCl (N-Desethyl Amiodarone-d4 HCl)
(2-butyl-1-benzofuran-3-yl)-[3,5-diiodo-4-[1,1,2,2-tetradeuterio-2-(ethylamino)ethoxy]phenyl]methanone:hydrochloride
[EINECS(EC#)]

200-659-6
[Molecular Formula]

C23H26ClI2NO3
[MDL Number]

MFCD08064190
[MOL File]

1189960-80-2.mol
[Molecular Weight]

653.72
Chemical PropertiesBack Directory
[Fp ]

9℃
[storage temp. ]

-20°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Light Brown
[Major Application]

clinical testing
[InChI]

1S/C23H25I2NO3.ClH/c1-3-5-9-20-21(16-8-6-7-10-19(16)29-20)22(27)15-13-17(24)23(18(25)14-15)28-12-11-26-4-2;/h6-8,10,13-14,26H,3-5,9,11-12H2,1-2H3;1H/i11D2,12D2;
[InChIKey]

OCQPMJVGWGJLLG-ZYMFQSNRSA-N
[SMILES]

Ic1c(c(cc(c1)C(=O)c2c3c([o]c2CCCC)cccc3)I)OC(C(NCC)([2H])[2H])([2H])[2H].Cl
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS02,GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H301+H311+H331-H370
[Precautionary statements ]

P210-P260-P280-P301+P310-P311
[Hazard Codes ]

F,T
[Risk Statements ]

11-23/24/25-39/23/24/25
[Safety Statements ]

7-16-36/37-45
[RIDADR ]

UN1230 - class 3 - PG 2 - Methanol, solution
[WGK Germany ]

1
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1
Hazard InformationBack Directory
[Uses]

A metabolite of Amiodarone, a non-selective ion channel blocker.
[General Description]

A Certified Spiking Solution?and stable-labeled internal standard for use in therapeutic drug monitoring analyses by LC/MS. N-Desethylamiodarone is the primary, active metabolite of amiodarone, an antiarrhythmic agent marketed as Pacerone?, Cordarone?, Aratac, or Atlansil. N-Desethylamiodarone and amiodarone are monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.
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