| Identification | Back Directory | [Name]
UV Cleavable Biotin-PEG2-Azide | [CAS]
1192802-98-4 | [Synonyms]
UV Cleavable Biotin-PEG2-N3
UV curable biotin polyethylene glycol azide | [Molecular Formula]
C38H51N7O9S | [MDL Number]
MFCD28505541 | [MOL File]
1192802-98-4.mol | [Molecular Weight]
781.93 |
| Hazard Information | Back Directory | [Uses]
UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. UV Cleavable Biotin-PEG2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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