| Identification | Back Directory | [Name]
3-(Bromomethyl)benzo[b]thiophene | [CAS]
1196-19-6 | [Synonyms]
3-(Bromomethyl)benzothiophene
3-(Bromomethyl)benzo[b]thiophene
3-(Bromomethyl)-1-benzothiophene
Benzo[b]thiophene, 3-(bromomethyl)- | [Molecular Formula]
C9H7BrS | [MDL Number]
MFCD00098683 | [MOL File]
1196-19-6.mol | [Molecular Weight]
227.12 |
| Chemical Properties | Back Directory | [Boiling point ]
311.3±17.0 °C(Predicted) | [density ]
1.593±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [form ]
solid |
| Hazard Information | Back Directory | [Synthesis]
B. Phosphorus tribromide (PBr3, 0.23 mL, 2.42 mmol) was added slowly and dropwise to a stirring solution of benzothiophene-3-ylmethanol (400 mg, 2.44 mmol) in ether (12 mL) at 0 °C. The reaction mixture was continued to be stirred at 0 °C for 30 min, then brought to room temperature and held for 45 min. The reaction mixture was poured into a mixture of ice water and ether, and the organic phase was separated, washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 3-(bromomethyl)benzo[b]thiophene as a light-colored solid (404 mg, 73% yield). | [References]
[1] Patent: WO2008/110793, 2008, A1. Location in patent: Page/Page column 111
[2] Patent: US2009/176996, 2009, A1. Location in patent: Page/Page column 15-16 |
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