| Identification | More | [Name]
2,5-Dimethylindole | [CAS]
1196-79-8 | [Synonyms]
2,5-DIMETHYL-1H-INDOLE
2,5-DIMETHYLINDOLE
1H-Indole, 2,5-dimethyl- | [EINECS(EC#)]
214-816-1 | [Molecular Formula]
C10H11N | [MDL Number]
MFCD00005621 | [Molecular Weight]
145.2 | [MOL File]
1196-79-8.mol |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white to pale pink or light brown solid | [Uses]
- Reactant in stereoselective preparation of substituted indoles via rhodium-catalyzed enantioselective coupling reaction of indoles with diazo compounds
- Reactant in stereoselective synthesis of indolines via palladium-catalyzed asymmetric hydrogenation of unprotected indoles
- Reactant in enantioselective synthesis of fluorene derivatives via Friedel-Crafts reactions
- Reactant in preparation of bis-indolyldihydroxybenzoquinones by addition indoles to dichlorobenzoquinone promoted by Bronsted acid
- Reactant in reaction with hydroxypyrazolines
|
| Questions And Answer | Back Directory | [Description]
2, 5-Dimethylindole is a kind of carbazole-system derived indole compound, which is valuable in the manufacturing of perfume. It is also a useful chemical intermediate. It is usually used as reactant in the following reaction: stereoselective synthesis of indolines via palladium-catalyzed asymmetric hydrogenation of unprotected indoles; stereoselective preparation of substituted indoles via rhodium-catalyzed enantioselective coupling reaction of indoles with diazo compounds; enantioselective synthesis of fluorene derivatives via Friedel-Crafts reactions; preparation of bis-indolyldihydroxybenzoquinones by addition indoles to dichlorobenzoquinone promoted by Bronsted acid; Reaction with hydroxypyrazolines.
| [Sources]
https://www.sigmaaldrich.com/catalog/product/aldrich/d166006?lang=en®ion=US
https://books.google.com/books?isbn=0470188073
|
|
|