ChemicalBook--->CAS DataBase List--->1196800-40-4

1196800-40-4

1196800-40-4 Structure

1196800-40-4 Structure
IdentificationBack Directory
[Name]

PTK0796 Methanesulfonate
[CAS]

1196800-40-4
[Synonyms]

OMadacycline (Mesylate)
PTK0796 Methanesulfonate
PTK-0796 Methanesulfonate
PTK 0796 Methanesulfonate
OMadacycline Methanesulfonate
AMadacycline (Methanesulfonate)
OMADACYCLINE METHANESULFONATE; PTK 0796 METHANESULFONATE; PTK-0796 METHANESULFONATE; PTK0796 METHANESULFONATE
[Molecular Formula]

C29H40N4O7.x(CH4O3S)
[MDL Number]

MFCD26142922
[MOL File]

1196800-40-4.mol
[Molecular Weight]

652.756
Chemical PropertiesBack Directory
[storage temp. ]

4°C, protect from light
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Description]

Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The primary effect of omadacycline is on bacterial protein synthesis, inhibiting protein synthesis with a potency greater than that of tetracycline. The binding site for omadacycline is similar to that for tetracycline.
[storage]

4°C, protect from light
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