| Identification | Back Directory | [Name]
L 659286 | [CAS]
119742-06-2 | [Synonyms]
286
L 659286
(6R,7S)-7α-Methoxy-4-(pyrrolizinocarbonyl)-3-[[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin)-3-yl]thio]methyl]cepham-3-ene 1,1-dioxide | [Molecular Formula]
C17H21N5O7S2 | [MOL File]
119742-06-2.mol | [Molecular Weight]
471.508 |
| Hazard Information | Back Directory | [Description]
L 659286 is a cephalosporin derivative. | [Uses]
L 659286 is an inhibitor of human polymorphonuclear leukocyte elastase (PMN elastase) (Ki=0.4 μM). Intratracheal injection of L 659286 can induce lung injury in hamsters. | [References]
[1] Pharmacological profile of the substituted beta‐lactam L‐659,286: A member of a new class of human PMN elastase inhibitors |
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