| Identification | Back Directory | [Name]
2''-Acetylastragalin | [CAS]
1206734-95-3 | [Synonyms]
2''-Acetylastragalin
4H-1-Benzopyran-4-one, 3-[(2-O-acetyl-β-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)- | [Molecular Formula]
C23H22O12 | [MDL Number]
MFCD23103591 | [MOL File]
1206734-95-3.mol | [Molecular Weight]
490.41 |
| Hazard Information | Back Directory | [Uses]
2’’-Acetylastragalin (Compound 2) is a compound isolated from the aerial parts of Delphinium staphisagria, with an IC50 value of 6.5 μM for Vero cells. 2’’-Acetylastragalin has trypanoidal activity[1]. | [Definition]
ChEBI: 2''-acetylastragalin is a kaempferol O-glucoside that is the 2''-acetyl derivative of astragalin (kaempferol 3-O-glucoside). Isolated from the aerial parts of Delphinium staphisagria, it exhibits trypanocidal activity. It has a role as a trypanocidal drug and a plant metabolite. It is a trihydroxyflavone, an acetate ester, a beta-D-glucoside, a monosaccharide derivative and a kaempferol O-glucoside. It is functionally related to a kaempferol 3-O-beta-D-glucoside. | [References]
[1] Marín C, et al. In vitro and in vivo trypanocidal activity of flavonoids from Delphinium staphisagria against Chagas disease. J Nat Prod. 2011 Apr 25;74(4):744-50. DOI:10.1021/np1008043 |
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