| Identification | More | [Name]
10-METHYLPHENOTHIAZINE | [CAS]
1207-72-3 | [Synonyms]
10-METHYLPHENOTHIAZINE
AKOS 93806
N-METHYLPHENOTHIAZINE
10-methyl-10h-phenothiazin
10-Methyl-10H-phenothiazine
9,10-Dibenzoisothiazine, 10-methyl-
Phenothiazide methyl derivative
Phenothiazine, 10-methyl-
2-Methyl Phenothiazine | [EINECS(EC#)]
214-896-8 | [Molecular Formula]
C13H11NS | [MDL Number]
MFCD00041836 | [Molecular Weight]
213.3 | [MOL File]
1207-72-3.mol |
| Chemical Properties | Back Directory | [Appearance]
slightly yellow to pale green crystalline powder | [Melting point ]
99-101 °C (lit.) | [Boiling point ]
341.6±12.0 °C(Predicted) | [density ]
1.1168 (rough estimate) | [refractive index ]
1.5700 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
0.56±0.20(Predicted) | [color ]
White to Light yellow | [Water Solubility ]
Insoluble in water. | [λmax]
310nm(CHCl3)(lit.) | [InChIKey]
QXBUYALKJGBACG-UHFFFAOYSA-N | [CAS DataBase Reference]
1207-72-3(CAS DataBase Reference) | [EPA Substance Registry System]
10H-Phenothiazine, 10-methyl- (1207-72-3) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
2934.30.5000 |
| Hazard Information | Back Directory | [Chemical Properties]
slightly yellow to pale green crystalline powder | [Uses]
They are used in pharmaceutical manufacturing especially antipsychotic drugs. Also used as a stabilizer against polymerization of acrylates. | [Definition]
ChEBI:10-methylphenothiazine is a member of phenothiazines. | [Purification Methods]
Recrystallise it (three times) from EtOH to give the -form (prisms). Recrystallisation from EtOH/*benzene gives the .-form (needles). It has also been purified by vacuum sublimation and is carefulmax 255nm (log 4.60) (pH 6.3) and 255nm in hexane. [Cymerman-Craig & Warburton Aust J Chem 9 294 1956, Beilstein 27 II 33, 27 III/IV 1215.] |
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