| Identification | Back Directory | [Name]
CTP-354 | [CAS]
1213669-91-0 | [Synonyms]
CTP-354
C-21191
EOS-60358
7-(tert-butyl-d9)-3-(2,5-difluorophenyl)-6-((1-methyl-1H-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolo[4,3-b]pyridazine
3-(2,5-difluorophenyl)-6-((1-methyl-1H-1,2,4-triazol-5-yl)methoxy)-7-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)-[1,2,4]triazolo[4,3-b]pyridazine
3-(2,5-difluorophenyl)-7-[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]-6-[(2-methyl-1,2,4-triazol-3-yl)methoxy]-[1,2,4]triazolo[4,3-b]pyridazine | [Molecular Formula]
C19H19F2N7O | [MDL Number]
MFCD28386315 | [MOL File]
1213669-91-0.mol | [Molecular Weight]
399.41 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMF: 3 mg/ml,DMSO: 3 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): insol | [form ]
A solid | [color ]
White to off-white | [InChI]
InChI=1S/C19H19F2N7O/c1-19(2,3)13-8-15-24-25-17(12-7-11(20)5-6-14(12)21)28(15)26-18(13)29-9-16-22-10-23-27(16)4/h5-8,10H,9H2,1-4H3 | [InChIKey]
BQDUNOMMYOKHEP-UHFFFAOYSA-N | [SMILES]
O(C1C(=CC2=NN=C(C3C=C(F)C=CC=3F)N2N=1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])CC1=NC=NN1C |
| Hazard Information | Back Directory | [Uses]
L-838417-d9 is the deuterium labeled L-838417. L-838417 is a subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1]. | [storage]
-20°C | [References]
[1] Hofmann M, et al. Assessment of the effects of NS11394 and L-838417, α2/3 subunit-selective GABA(A) [corrected] receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function [published correction appears in Behav Pharmacol. 2013 Apr;24(2):153]. Behav Pharmacol. 2012;23(8):790-801. DOI:10.1097/FBP.0b013e32835a7c7e |
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| Company Name: |
SPIRO PHARMA
|
| Telephone: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
InvivoChem
|
| Telephone: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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