| Identification | Back Directory | [Name]
5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE | [CAS]
1214-79-5 | [Synonyms]
Dimethylamiloride
DMA HYDROCHLORIDE
5-dimethylamiloride
5-(N,N-Dimethyl)-amiloride
5-(N,N-DIMETHYL)AMILORIDE HCL
5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
AMILORIDE, 5-(N,N-DIMETHYL)-, HYDROCHLORIDE
3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazinamide
3-Amino-5-(dimethylamino)-6-chloro-N-(diaminomethylene)pyrazinecarboxamide
6-Chloro-3-amino-5-(dimethylamino)-N-(diaminomethylene)-2-pyrazinecarboxamide
N-(Diaminomethylene)-3-amino-5-(dimethylamino)-6-chloropyrazine-2-carboxamide
3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide
2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)-
3-Amino-5-(N,N-dimethylamino)-6-chloro-N-(aminoiminomethyl)-2-pyrazinecarboxamide
3-azanyl-N-[bis(azanyl)methylidene]-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide
3-amino-n-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride
3-AMINO-N-(AMINOIMINOMETHYL)-5-(DIMETHYLAMINO)-6-CHLORO-PYRAZINE-CARBOXAMIDE HYDROCHLORIDE
DMA, 3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride | [Molecular Formula]
C8H12ClN7O | [MDL Number]
MFCD00069207 | [MOL File]
1214-79-5.mol | [Molecular Weight]
257.68 |
| Chemical Properties | Back Directory | [Melting point ]
216-217 °C | [density ]
1.68±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Yellow solid. | [pka]
8.66±0.46(Predicted) | [color ]
Light yellow to yellow | [InChI]
1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H | [InChIKey]
IIUPTHVVXMBJMQ-UHFFFAOYSA-N | [SMILES]
Cl.CN(C)c1nc(N)c(nc1Cl)C(=O)\N=C(\N)N |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [RIDADR ]
2811 | [WGK Germany ]
- | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain. | [Biochem/physiol Actions]
Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM. |
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