| Identification | Back Directory | [Name]
SULFANITRAN | [CAS]
122-16-7 | [Synonyms]
APNPS
NSC-77120
NSC 217299
SULFANITRAN
sulfanitran85+%
Sulfanitran Standard
sulfanitranapprox.85%
sulfanitran approx. 85%
Sulfanitran solution,100ppm
N4-Acetyl-4'-nitrosulfanilanilide
ACETYL[P-NITROPHENYL]SULFANILAMIDE
4-(4-nitrophenylsulfamoyl)acetanilide
SULFANITRAN VETRANAL (N-(4-ACETYLAMINOBE
4'-[(p-Nitrophenyl)sulfamoyl]acetanilide
N4-ACETYL-N1-(4-NITROPHENYL)SULFANILAMIDE
N4-Acetyl-N1-(p-nitrophenyl)sulfanilaMide
Sulfanitran Solution in Methanol, 1000μg/mL
N-[4-[(4-nitrophenyl)sulfamoyl]phenyl]acetamide
N-[4-[(4-nitrophenyl)sulfamoyl]phenyl]ethanamide
N4-ACETYL-N1-(4-NITROPHENYL)-SULFANILAMIDE, TECH.
N-(4-(N-(4-nitrophenyl)sulfamoyl)phenyl)acetamide
Sulfanitran,N4-Acetyl-N1-(4-nitrophenyl)sulfanilamide
Acetamide, N-[4-[[(4-nitrophenyl)amino]sulfonyl]phenyl]- | [Molecular Formula]
C14H13N3O5S | [MDL Number]
MFCD00024598 | [MOL File]
122-16-7.mol | [Molecular Weight]
335.34 |
| Chemical Properties | Back Directory | [Melting point ]
239-240° (Kaufmann); mp 264° (Shepherd) | [density ]
1.500±0.06 g/cm3(Predicted) | [storage temp. ]
0-6°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
7.42±0.10(Predicted) | [color ]
yellow to greenish-yellow | [BRN ]
2952955 | [Major Application]
clinical testing | [InChI]
1S/C14H13N3O5S/c1-10(18)15-11-4-8-14(9-5-11)23(21,22)16-12-2-6-13(7-3-12)17(19)20/h2-9,16H,1H3,(H,15,18) | [InChIKey]
GWBPFRGXNGPPMF-UHFFFAOYSA-N | [SMILES]
CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)[N+]([O-])=O |
| Hazard Information | Back Directory | [Chemical Properties]
Yellowish Green Solid | [Uses]
anti-hypertensive | [Uses]
Sulfanitran is a sulfanomide derivative used as an anticoccidial drug. Sulfanitran is added to the drinking water of chickens as an aid in the treatment of coccidiosis caused by E. tenella, E. necatrix, and E. acervulina. | [Definition]
ChEBI: N-[4-[(4-nitrophenyl)sulfamoyl]phenyl]acetamide is a sulfonamide. | [Synthesis]
GENERAL METHOD: To a solution of 4-nitroaniline (1 eq.) in pyridine (1.6 mL/mmol) was slowly added p-acetamidobenzenesulfonyl chloride (1.1 eq.) and the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction was quenched with water and extracted three times with ethyl acetate (EtOAc). The organic layers were combined and washed sequentially with 0.5 N HCl three times, water three times and saturated saline once. The organic phase was dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give N-(4-(N-(4-nitrophenyl)aminosulfonyl)phenyl)acetamide as a solid product. | [References]
[1] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 18, p. 4426 - 4430
[2] Patent: US2282769, 1939,
[3] Journal of the American Chemical Society, 1939, vol. 61, p. 613,616
[4] DRP/DRBP Org.Chem.,
[5] Canadian Journal of Research, Section B: Chemical Sciences, 1942, vol. 20, p. 5,7, 9 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
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| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
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