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1227678-26-3

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1227678-26-3 Structure

1227678-26-3 Structure
IdentificationBack Directory
[Name]

CEP-32496
[CAS]

1227678-26-3
[Synonyms]

CEP-32496
CEP-32496 HCl salt
CEP-32496 USP/EP/BP
RXDX105 hydrochloride
RXDX-105 hydrochloride
RXDX 105 hydrochloride
CEP32496 hydrochloride
CEP 32496 hydrochloride
Agerafenib hydrochloride
CEP-32496 (hydrochloride)
Agerafenib (CEP-32496) HCl
Agerafenib (CEP-32496) hydrochloride
CEP 32496 HYDROCHLORIDE; CEP32496 HYDROCHLORIDE
1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxaz
1-(3-(6,7-diMethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-Methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride
N-[3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]phenyl]-N'-[5-(2,2,2-trifluoro-1,1-dimethylethyl)-3-isoxazolyl]urea hydrochloride
CEP 32496 HYDROCHLORIDE;CEP32496 HYDROCHLORIDE;RXDX105 HYDROCHLORIDE;RXDX 105 HYDROCHLORIDE;RXDX-105 HYDROCHLORIDE;AGERAFENIB HYDROCHLORIDE
[Molecular Formula]

C24H23ClF3N5O5
[MDL Number]

MFCD22124523
[MOL File]

1227678-26-3.mol
[Molecular Weight]

553.918
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Powder
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

CEP 32496 is an orally active BRAFV600E inhibitor with selective cellular and in vivo antitumor activity.
[target]

wild-type BRAF
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