| Identification | Back Directory | [Name]
Seractide | [CAS]
12279-41-3 | [Synonyms]
ACTH
ACTH 1-39
Seractide
Seractide ACTH
CORTICOTROPHIN
CORTICOTROPIN A
Seractide acetate
ACTH (1-39), HUMAN
Seractide USP/EP/BP
CORTICOTROPIN (HUMAN)
M.W. 4541.07 C207H308N56O58S
ACTH(1-39) CORTICOTROPIN, HUMAN
ADRENOCORTICOTROPIC HORMONE HUMAN
ACTH (1-39) (huMan)
Corticotropin
PCorticotropin (Human) CAS 12279-41-3
SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
adrenocorticotropic hormone fragment 1-39
Adrenocorticotropic Hormone (ACTH) (1-39)
ADRENOCORTICOTROPIC HORMONE (1-39) (HUMAN)
Adrenocorticotropic Hormone (ACTH) (1-39), human
Adrenocorticotropic hormone fragment 1-39, ≥97% (HPLC)
H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH
SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE
H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH
SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE HUMAN
REF DUPL: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe
ACTH (1-39) (human) trifluoroacetate salt H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH trifluoroacetate salt
L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-asparaginylglycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine | [EINECS(EC#)]
634-154-0 | [Molecular Formula]
C207H308N56O58S1 | [MDL Number]
MFCD00145721 | [MOL File]
12279-41-3.mol | [Molecular Weight]
4541.07 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
H2O: 1 mg/mL, clear, colorless
| [form ]
Solid | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH |
| Hazard Information | Back Directory | [Uses]
Hormone (adrenocorticotropic). | [Brand name]
Acthar Gel-Synthetic (Armour). | [General Description]
Adrenocorticotropic hormone (ACTH) is a 303-amino acid hormone protein, which is located at human chromosome 2p23.3. | [Biochem/physiol Actions]
Adrenocorticotropic hormone (ACTH) stimulates melanocortin receptor (MC1R to MC5R).It is implicated in the production of α-melanocyte-stimulating hormone (α-MSH). Hypomethylation of ACTH promoter region in thymic carcinoids is associated with ectopic adrenocorticotropic hormone syndrome. Mutations in this gene are associated with aberrant fusion protein and impairing melanocortin signaling in hypoadrenalism. Dysregulation of ACTH leads to Cushing disease. | [storage]
Store at -20°C |
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