| Identification | Back Directory | [Name]
Linderaspirone A | [CAS]
1235126-46-1 | [Synonyms]
Linderaspirone A
(8R,16R)-rel-2,3,6,11,12,14-Hexamethoxy-8,16-diphenyldispiro[4.3.4.3]hexadeca-2,6,11,14-tetraene-1,4,10,13-tetrone
Dispiro[4.3.4.3]hexadeca-2,6,11,14-tetraene-1,4,10,13-tetrone, 2,3,6,11,12,14-hexamethoxy-8,16-diphenyl-, (8R,16R)-rel- | [Molecular Formula]
C34H32O10 | [MOL File]
1235126-46-1.mol | [Molecular Weight]
600.61 |
| Chemical Properties | Back Directory | [Boiling point ]
826.5±65.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
Linderaspirone A is a natural compound that can be isolated from the roots of Lindera aggregate. Linderaspirone A shows significant inhibitory effects on the production of prostaglandin E2 (PGE2),TNF-α, and IL-6 [1][2]. | [References]
[1] Lin Chen, et al. Lindera cyclopentenedione intermediates from the roots of Lindera aggregate. RSC Adv. 2018 May 16;8(32):17898-17904. DOI:10.1039/c8ra03094d
[2] Chi-Su Yoon, et al. Effects of Compounds Isolated from Lindera erythrocarpa on Anti-Inflammatory and Anti-Neuroinflammatory Action in BV2 Microglia and RAW264.7 Macrophage. Int J Mol Sci. 2022 Jun 27;23(13):7122. DOI:10.3390/ijms23137122 |
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