| Identification | Back Directory | [Name]
QNZ-46 | [CAS]
1237744-13-6 | [Synonyms]
QNZ46
QNZ-46
QNZ 46
CS-2059
CS-2438
QNZ 46;QNZ-46
QNZ-46;QNZ 46;QNZ46
QNZ46 - CAS 1237744-13-6 - Calbiochem
4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic Acid
Benzoic acid, 4-[6-methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]- | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C24H17N3O6 | [MDL Number]
MFCD22666391 | [MOL File]
1237744-13-6.mol | [Molecular Weight]
443.41 |
| Chemical Properties | Back Directory | [Melting point ]
>260 °C | [Boiling point ]
705.8±70.0 °C(Predicted) | [density ]
1.37±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO: soluble5mg/mL (warmed; clear solution) | [form ]
Yellow powder | [pka]
4.28±0.10(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
QZN-46 is a known antagonist, or non-selective inhibitor, for NDMA-selective glutamate receptors. | [Biological Activity]
QNZ46 is a noncompetitive inhibitor of GluN2C/D containing NMDA receptors. KD and IC50 values for binding and inhibition of GluN1/Glun2D receptors by QNZ46 are 4.9 and 3.9 μMrespectively. QNZ46 does not compete for binding of glutamate or glycinebut QNZ46 receptor binding requires the binding of glutamate to the GluN2 subunit. | [storage]
room temperature |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
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