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123852-08-4

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123852-08-4 Structure

123852-08-4 Structure
IdentificationBack Directory
[Name]

NH-(m-PEG4)2
[CAS]

123852-08-4
[Synonyms]

(mPEG4)2-NH
NH-(m-PEG4)2
NH-bis(m-PEG4)
N,N-bis(tetraethyleneglycol-monomethylether)amine
2,5,8,11-Tetraoxatridecan-13-amine, N-3,6,9,12-tetraoxatridec-1-yl-
[Molecular Formula]

C18H39NO8
[MDL Number]

MFCD28015764
[MOL File]

123852-08-4.mol
[Molecular Weight]

397.5
Chemical PropertiesBack Directory
[solubility ]

Soluble in Water, DMSO, DCM, DMF
Hazard InformationBack Directory
[Description]

NH-bis(m-PEG4) is a PEG building block containing an amino (NH2) group to be reactive with carboxylic acids or activated NHS esters, carbonyls.
[Uses]

NH-bis(m-PEG4) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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