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63721-14-2

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63721-14-2 Structure

63721-14-2 Structure
IdentificationBack Directory
[Name]

NH-(PEG3-OH)2
[CAS]

63721-14-2
[Synonyms]

Ho-apeg8-oh
NH-bis-PEG4
NH-(PEG3-OH)2
NH-bis(PEG3-OH)
3,6,9,15,18,21-Hexaoxa-12-azatricosane-1,23-diol
[Molecular Formula]

C16H35NO8
[MDL Number]

MFCD29912667
[MOL File]

63721-14-2.mol
[Molecular Weight]

369.45
Chemical PropertiesBack Directory
[Boiling point ]

482.3±40.0 °C(Predicted)
[density ]

1.104±0.06 g/cm3(Predicted)
[storage temp. ]

Storage temp. 2-8°C
[form ]

Solid
[pka]

14.06±0.10(Predicted)
[color ]

Off-white to light brown
Hazard InformationBack Directory
[Description]

NH-bis(PEG3-OH) is a mall PEG molecule with a central amino group and two terminal hydroxyl groups. The amino group is reactive with activated NHS esters to form a stable amide bond.
[Uses]

NH-bis-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

NH-(PEG3-OH)2(63721-14-2)1HNMR
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