| Identification | Back Directory | [Name]
(3S,5R)-Rosuvastatin | [CAS]
1242184-42-4 | [Synonyms]
5R)-Rosuvastatin
(3S,5R)-Rosuvastatin
Rosuvastatin calcium-8
Rosuvastatin Impurity G
(3S,5R,6E)-Rosuvastatin
Rosuvastatin EP Impurity G
*Buprenorphine Impurity 17
Rosuvastatin impurity G CRS
Rosuvastatin Acid Enantiomer
Rosuvastatin EP Imp G (acid)
3S,5R-Rosuvastatin calcium salt
Rosuvastatin (3S,5R) enantiomer
Rosuvastatin EP impurity G(3S5R)
(3S,5R)-Rosuvastatin Sodium Salt
(3S,5R) Rosuvastatin,(3S,5R)Rosuvastatin
Rosuvastatin EP Impurity G (Calcium Salt)
Rosuvastatin Calcium EP Impurity G (Calcium Salt)
Rosuvastatin (3S,5R) Enantiomer (as diisopropylamine salt)
Rosuvastatin Impurity 11 Monomer(Rosuvastatin EP Impurity G Monomer)
Rosuvastatin EP Impurity G / Rosuvastatin Related Compound D / 3S, 5R Rosuvastatin
(3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
(3s,5r,6e)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, (3S,5R,6E)-
(3S,5R)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxy-6(E)-heptenoic acid calcium salt
(3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid, calcium salt (2:1)
Rosuvastatin EP Impurity G/ Rosuvastatin Related Compund D (Rosuvastatin Calcium Enantiomer/ enti-Rosuvastatin/ Rosuvastatin (3S,5R)-Isomer)
Rosuvastatin impurity G (Y0001722)Q: What is
Rosuvastatin impurity G (Y0001722) Q: What is the CAS Number of
Rosuvastatin impurity G (Y0001722)
((3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethyl sulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II)（Rosuvastatin EP Impurity G）
(3S,5R)-Rosuvastatin CalciumQ: What is
(3S,5R)-Rosuvastatin Calcium Q: What is the CAS Number of
(3S,5R)-Rosuvastatin Calcium Q: What is the storage condition of
(3S,5R)-Rosuvastatin Calcium Q: What are the applications of
(3S,5R)-Rosuvastatin Calcium | [Molecular Formula]
C22H28FN3O6S | [MDL Number]
MFCD28579810 | [MOL File]
1242184-42-4.mol | [Molecular Weight]
481.54 |
| Chemical Properties | Back Directory | [Boiling point ]
745.6±70.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [solubility ]
soluble in Methanol, Water | [form ]
Solid | [pka]
4.25±0.10(Predicted) | [color ]
Off-White to Pale Yellow | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
Rosuvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. | [Uses]
(3S,5R,6E)-Rosuvastatin is an isomer of Rosuvastatin(R700500), an impurity which acts as a selective, competitive HMG-CoA reductase inhibitor. | [Biological Activity]
(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels. |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|