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1244967-98-3

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1244967-98-3 Structure

1244967-98-3 Structure
IdentificationBack Directory
[Name]

Pizuglanstat
[CAS]

1244967-98-3
[Synonyms]

Pizuglanstat
Pizuglanstat (TAS-205)
inhibit,Prostaglandin Receptor,Pizuglanstat,Inhibitor
1-Piperazinecarboxamide, 4-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-N-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-
[Molecular Formula]

C27H36N6O4
[MOL File]

1244967-98-3.mol
[Molecular Weight]

508.61
Chemical PropertiesBack Directory
[Boiling point ]

808.3±65.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 12.5 mg/mL (24.58 mM; Need ultrasonic)
[form ]

Solid
[pka]

13.73±0.70(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

Pizuglanstat (compound 3) is a prostaglandin D synthase inhibitor with an IC50 of 76 nM for human hematopoietic prostaglandin D synthases (H-PGDS). Pizuglanstat can be used for myodegenerative disease research, such as muscular dystrophy[1].
[IC 50]

DP
[References]

[1] Yoshihiro Urade, et al. Piperazine compound capable of inhibiting prostaglandin D synthase. US8865714B2.
Spectrum DetailBack Directory
[Spectrum Detail]

Pizuglanstat(1244967-98-3)1HNMR
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