| Identification | More | [Name]
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole | [CAS]
124750-51-2 | [Synonyms]
5-(4'-BROMOMETHYL-1,1'-BIPHENYL-2-YL)-1-TRIPHENYLMETHYL-1H-TETRAZOLE
5-(4'-BROMOMETHYL-BIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE
N-(Triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole
N-(TRIPHENYLMETHYL)-5-(4'-BROMOMETHYLBIPHENYL-2-YL) TETRAZOLE
1H-Tetrazole, 5-[4'-(bromomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-
Trityl tetrazole bromomethyl biphenyl
5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-
5-[4'-(Bromomethyl)[1,1'-Biphenyl]-1-(Triphenylmethyl)Tetrazole]
N-(Triphenylmethyl)C5-(4'-Bromomethylbiphenyl-2Yl)Tetrazole
2-(N-Triphenylmethyltetrazolyl)-4-Bromomethylbiphenyl)97%
Valsartan intermediate
5-[4Bromomethyl-(1,1biphenyl)-2-yl]-1-triphenylmethyltetrazole
N-(TRIPHENYLMETHYL)-5-(4''-BROMOMETHYLBIPHENYL-2-YL-)TETRAZOLE(BBTT)
(TRIPHENYLMETHYL)TETRAZOLE
5-[4'-bromomethyl-1,1'-biphenyl-2-yl]-1-trityl-1H-tetrazole
5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-1H-TETRAAZOLE
N-(Triphenylmethyl)-5-(4’-bromomethylbiphenyl-2-yi-)tetrazole
n-(triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole | [EINECS(EC#)]
603-010-9 | [Molecular Formula]
C33H25BrN4 | [MDL Number]
MFCD00665221 | [Molecular Weight]
557.48 | [MOL File]
124750-51-2.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
152-155°C | [Boiling point ]
61°C/12mmHg(lit.) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Soluble in Chloroform and Methanol (Sparingly) | [form ]
Solid | [pka]
0.29±0.10(Predicted) | [color ]
White | [Usage]
An intermediate in the synthesis of Losartan and Valsartan | [Detection Methods]
HPLC | [Stability:]
Moisture Sensitive | [InChI]
InChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-36-37-38(32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2 | [InChIKey]
ZTFVTXDWDFIQEU-UHFFFAOYSA-N | [SMILES]
N1(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C(C2=CC=CC=C2C2=CC=C(CBr)C=C2)=NN=N1 | [CAS DataBase Reference]
124750-51-2(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole(124750-51-2) is an intermediate in the synthesis of Losartan and Valsartan. Utilized for various purposes, 5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole has found application as a fluorescent probe to identify DNA damage. It serves as a photosensitizer in photodynamic therapy and acts as a catalyst in polymer synthesis. Furthermore, this compound functions as a fluorescent label to detect proteins and as a fluorescent indicator to detect metal ions.
| [Chemical Properties]
Off-White Solid | [Uses]
An intermediate in the synthesis of Losartan and Valsartan | [Application]
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole is an important pharmaceutical intermediate. It can be used in the preparation of olmesartan medoxomil key intermediates, Losartan potassium, Valsartan, Candesartan and molecular sieve catalysts. | [Hazard]
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole has an acute toxin and is irritating to skin and eyes. | [References]
[1] HAI Z. Determination of the related substances in N-triphenylmethyl-5-(4’-bromomethylbiphenyl-2-yl-) terazole by HPLC[J]. West China Journal of Pharmaceutical Sciences, 2015. |
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