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124750-51-2

124750-51-2 Structure

124750-51-2 Structure
IdentificationMore
[Name]

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
[CAS]

124750-51-2
[Synonyms]

5-(4'-BROMOMETHYL-1,1'-BIPHENYL-2-YL)-1-TRIPHENYLMETHYL-1H-TETRAZOLE
5-(4'-BROMOMETHYL-BIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE
N-(Triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole
N-(TRIPHENYLMETHYL)-5-(4'-BROMOMETHYLBIPHENYL-2-YL) TETRAZOLE
1H-Tetrazole, 5-[4'-(bromomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-
Trityl tetrazole bromomethyl biphenyl
5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-
5-[4'-(Bromomethyl)[1,1'-Biphenyl]-1-(Triphenylmethyl)Tetrazole]
N-(Triphenylmethyl)C5-(4'-Bromomethylbiphenyl-2Yl)Tetrazole
2-(N-Triphenylmethyltetrazolyl)-4-Bromomethylbiphenyl)97%
Valsartan intermediate
5-[4Bromomethyl-(1,1biphenyl)-2-yl]-1-triphenylmethyltetrazole
N-(TRIPHENYLMETHYL)-5-(4''-BROMOMETHYLBIPHENYL-2-YL-)TETRAZOLE(BBTT)
(TRIPHENYLMETHYL)TETRAZOLE
5-[4'-bromomethyl-1,1'-biphenyl-2-yl]-1-trityl-1H-tetrazole
5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-1H-TETRAAZOLE
N-(Triphenylmethyl)-5-(4’-bromomethylbiphenyl-2-yi-)tetrazole
n-(triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole
[EINECS(EC#)]

603-010-9
[Molecular Formula]

C33H25BrN4
[MDL Number]

MFCD00665221
[Molecular Weight]

557.48
[MOL File]

124750-51-2.mol
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

152-155°C
[Boiling point ]

61°C/12mmHg(lit.)
[density ]

1.28±0.1 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

Soluble in Chloroform and Methanol (Sparingly)
[form ]

Solid
[pka]

0.29±0.10(Predicted)
[color ]

White
[Usage]

An intermediate in the synthesis of Losartan and Valsartan
[Detection Methods]

HPLC
[Stability:]

Moisture Sensitive
[InChI]

InChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-36-37-38(32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2
[InChIKey]

ZTFVTXDWDFIQEU-UHFFFAOYSA-N
[SMILES]

N1(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C(C2=CC=CC=C2C2=CC=C(CBr)C=C2)=NN=N1
[CAS DataBase Reference]

124750-51-2(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H315-H319-H228
[Precautionary statements ]

P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313
[RIDADR ]

UN 2811 6.1/PG III
[REACH Registrations]

Active
[HazardClass ]

6.1
[PackingGroup ]

III
Hazard InformationBack Directory
[Description]

5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole(124750-51-2) is an intermediate in the synthesis of Losartan and Valsartan. Utilized for various purposes, 5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole has found application as a fluorescent probe to identify DNA damage. It serves as a photosensitizer in photodynamic therapy and acts as a catalyst in polymer synthesis. Furthermore, this compound functions as a fluorescent label to detect proteins and as a fluorescent indicator to detect metal ions.
[Chemical Properties]

Off-White Solid
[Uses]

An intermediate in the synthesis of Losartan and Valsartan
[Application]

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole is an important pharmaceutical intermediate. It can be used in the preparation of olmesartan medoxomil key intermediates, Losartan potassium, Valsartan, Candesartan and molecular sieve catalysts.
[Hazard]

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole has an acute toxin and is irritating to skin and eyes.
[References]

[1] HAI Z. Determination of the related substances in N-triphenylmethyl-5-(4’-bromomethylbiphenyl-2-yl-) terazole by HPLC[J]. West China Journal of Pharmaceutical Sciences, 2015.
Spectrum DetailBack Directory
[Spectrum Detail]

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole(124750-51-2)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

124750-51-2(sigmaaldrich)
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