| Identification | Back Directory | [Name]
3,3-BIS(P-HYDROXYPHENYL)OXINDOLE | [CAS]
125-13-3 | [Synonyms]
isolax
lavema
recolon
neodrast
normalax
hoscolax
propellax
veripaque
phenolisatin
OXYPHENISATIN
diphenolisatin
oxyphenisatine
isatinbisphenol
TIMTEC-BB SBB008302
4,4’-dihydroxydiphenylisatin
3,3-BIS(4-HYDROXPHENYL)OXINDOLE
3,3-BIS(P-HYDROXYPHENYL)OXINDOLE
3,3-BIS(4-HYDROXYPHENYL)OXINDOLE
3,3-bis(p-hydroxyphenyl)-2-indolinon
3,3-bis(p-hydroxyphenyl)-2-indolinone
3,3-bis(4-hydroxyphenyl)indolin-2-one
3,3-BIS(4-HYDROXYPHENYL)-2-INDOLINONE
3,3-Bis(4-hydroxyphenyl)indoline-2-one
3,3-bis(4-hydroxyphenyl)-1H-indol-2-one
3,3-Bis(4-Hydroxsyphenyl)-2(3H)-Indolone
3,3-BIS(P-HYDROXYPHENYL)OXINDOLE USP/EP/BP
1,3-dihydro-3,3-bis(4-hydroxyphenyl)-2h-indol-2-on
1,3-dihydro-3,3-bis(4-hydroxyphenyl)-2h-indol-2-one
3,3-Bis(4-hydroxyphenyl)-1,3-dihydro-2H-indol-2-one
2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)- | [EINECS(EC#)]
204-728-1 | [Molecular Formula]
C20H15NO3 | [MDL Number]
MFCD00022794 | [MOL File]
125-13-3.mol | [Molecular Weight]
317.34 |
| Chemical Properties | Back Directory | [Melting point ]
260-261 °C | [Boiling point ]
562.9±50.0 °C(Predicted) | [density ]
1.352±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 28 mg/mL (88.23 mM) | [form ]
Solid | [pka]
9.42±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Chemical Properties]
Crystallization. Melting point>260℃. | [Uses]
Oxyphenisatine is a diphenolic laxative and it’s prodrug Oxyphenisatine acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468 by inducing multifaceted cell starvation response, which ultimately induces programmed cell death. | [Definition]
ChEBI: Oxyphenisatine is a member of indoles. | [in vivo]
Toxicity studies demonstrate that mice tolerate IP administration of OXY at 300 mg/kg once daily or 200 mg/kg twice daily. Administration of OXY at 300 mg/kg IP once daily for 10 days results in significantly smaller tumors from day 33 to day 52[1]. |
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