| Identification | Back Directory | [Name]
3'-Deoxy-3'-fluoro-5-trifluoroMethyluridine | [CAS]
439579-21-2 | [Synonyms]
3'-Deoxy-3'-fluoro-5-trifluoroMethyluridine
3'-Deoxy-3'-fluoro-5-trifluoroMethyluridine
Uridine, 3'-deoxy-3'-fluoro-5-(trifluoromethyl)- (9CI) | [Molecular Formula]
C10H10F4N2O5 | [MOL File]
439579-21-2.mol | [Molecular Weight]
314.19 |
| Hazard Information | Back Directory | [Uses]
3’-Deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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