ChemicalBook--->CAS DataBase List--->125372-33-0

125372-33-0

125372-33-0 Structure

125372-33-0 Structure
IdentificationBack Directory
[Name]

AIDS029690
[CAS]

125372-33-0
[Synonyms]

Rp 55778
Acopafant
AIDS029690
UNII-H1T03Z1G60
1H,3H-Pyrrolo[1,2-C]thiazole-7-carboxamide, 3-(3-pyridinyl)-, (3R)-
[Molecular Formula]

C12H11N3OS
[MDL Number]

MFCD00887930
[MOL File]

125372-33-0.mol
[Molecular Weight]

245.3
Chemical PropertiesBack Directory
[Boiling point ]

516.4±50.0 °C(Predicted)
[density ]

1.49±0.1 g/cm3(Predicted)
[pka]

16.43±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Acopafant (Dacopafant; RP 55778) is a potent platelet-activating factor antagonist. Acopafant inhibits the induction of human immunodeficiency virus (HIV) expression in chronically infected cells. Acopafant has the potential for the research of HIV infection[1].
[References]

[1] Weissman D, . A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells. Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2537-41. DOI:10.1073/pnas.90.6.2537
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