| Identification | Back Directory | [Name]
6-HYDROXY BUSPIRONE | [CAS]
125481-61-0 | [Synonyms]
BMY 28674
BMS 528215
6-HYDROXY BUSPIRONE
Buspirone 6-Hydroxy Metabolite
6-Hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9- dione | [Molecular Formula]
C21H31N5O3 | [MDL Number]
MFCD08063642 | [MOL File]
125481-61-0.mol | [Molecular Weight]
401.5 |
| Chemical Properties | Back Directory | [Appearance]
Off-White to Pale Yellow Solid | [Melting point ]
96-99°C | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [InChI]
1S/C21H31N5O3/c27-17-16-21(6-1-2-7-21)18(28)19(29)26(17)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9,18,28H,1-4,6-7,10-16H2 | [InChIKey]
KOZNAHJIJGCFJJ-UHFFFAOYSA-N | [SMILES]
O=C1C(O)C2(CCCC2)CC(N1CCCCN(CC3)CCN3C4=NC=CC=N4)=O |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White to Pale Yellow Solid | [Uses]
It is a major active metabolite of Buspirone (B689850). | [Definition]
ChEBI: 6-hydroxy buspirone is a N-arylpiperazine. | [IC 50]
Rat 5-HT1A Receptor: 4 μM (EC50); D2 Receptor: 3.1 μM (IC50); D3 Receptor: 4.9 μM (IC50); D4 Receptor: 0.85 μM (IC50); Rat 5-HT1A Receptor: 1 μM (EC50) |
| Safety Data | Back Directory | [WGK Germany ]
WGK 2 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2 |
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|